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Liquid Chromatography-Mass Spectrometry

The highly versatile Liquid Chromatography-Mass Spectrometry instrument illustrated here can separate and quantify analytes as diverse as vitamins and minerals, mycotoxins and illegal dyes.

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Transcript

The state-of-the-art Liquid Chromatography-Mass Spectrometry instrument illustrated here is seen in use for analysis of acrylamide.


In this example, the acrylamide is extracted into acetonitrile ready for presentation to the instrument.


The chromatography columns used are different for different analytes.


The column can perform separations of mixtures of substances and the purified analytes are then quantified by the mass spectrometry function.


The machine is extremely sensitive, with a limit of detection of around 100 parts per trillion.


It is also very flexible in the types of analytes it can be used for - from vitamins and minerals, through mycotoxins and other contaminants to illegal dyes.


Its speed of throughput means that it can separate and quantify around 100 pesticides in about 10 minutes.


It can also cope with a wide range of molecular sizes - from elements through to organic compounds with molecular weights of several thousands.